ProjektportalDevelopment of peptides and proteins for molecular imaging and targeted therapy of prostate cancedr
Terrmin
VT22
Beskrivning
The Theranostics group focuses on molecular design and pre-clinical characterization of peptides and proteins for molecular imaging and targeted therapy of prostate cancer. We develop diagnostic radiolabeled imaging agents for single photon emission computed tomography (SPECT) and positron emission tomography (PET), as well as therapeutic agents with differen mechanism of action, e.g. cytoctatic biodrug, targeting drugs loaded with drugs, toxins, therapeutic radionuclides.
Master project in our group includes training in radiation protection, differnt methods in radiolabeling of peptides and proteins, in vitro (determination of affinity, spercificity, IC50, internalization rate, therapeutic efficacy) and in vivo (investigation of targeting and biodistribution) characterization of drug candidates. Master students will work in actual research projects together with PhD students and postdocs. Master students can take a FELASA course during the project.
For more information, contact Anna Orlova, anna.orlova@ilk.uu.se, and/or visit https://www.ilk.uu.se/forskargrupper/theranostics/
Huvudområde
Läkemedelsutveckling
Ämne
Molekylär avbildning
Typ
Laborativ studie
Företag
Institutionen för Läkemedelskemi
Ort/Plats
Uppsala
Handledarens namn
Anna Orlova
Handledarens e-post
anna.orlova@ilk.uu.se
Institution
Program
Kurs
Omfattning/hp
30hp
Hur många studenter kan antagas för detta projekt?
1