Ingrid Glimelius

Department of Immuno-oncology, Genetics and Pathology

v.6

Rudbeck, Waldenströmsalen

5 days

This is a course for doctoral students (healthcare professionals/biomedical scientists/physicians/pharmacists). Pharmacists should note that there is a strong focus on the clinical component.
The course is delivered through seminars and lectures, as well as a group project including its presentation, over the course of one week (five days). Some courses may be in Swedish.

After completed the course, the student should be able to:

* Provide examples of different types of immuno-oncology drugs currently used in clinical practice as well as those under preclinical development
* Illustrate and explain how various types of immunotherapies function biologically
* Understand the types of side effects that immuno-oncology drugs may cause and how to manage them
* Understand how the tumor microenvironment can influence a patient’s response to therapy
* Propose a design for a clinical immunotherapy study

This is a course for doctoral students/healthcare professionals/pharmacists/physicians. The course aims to provide students with knowledge about immuno-oncology in both preclinical development and clinical practice. It seeks to enhance students’ understanding of which immuno-oncology agents are currently used in clinical settings, how non-classical immuno-oncology agents can influence immune responses against tumors, and which future immuno-oncology agents are under development but not yet in clinical use.
The course will also examine the mechanisms behind the effects of immuno-oncology drugs, resistance mechanisms, and the expected side-effect profiles of these agents, including how such side effects should be managed. Examples of concepts addressed include antigen presentation and pseudoprogression. A background on the immune system and the tumor microenvironment is also included.

Not specified

The examination will consist of completing and presenting a group assignment. The examination will be supervised by Ingrid Glimelius, Gustav Ullenhag, and Tanja Lövgren.
Grading scale: Pass/Fail.

Lecture notes, scientific articles distributed prior to the course, as well as instructions, links to videos and articles that recap the immunology field.

Gustav Ullenhag, Department of Immunology, Genetics and Pathology, Uppsala University
Ingrid Glimelius, Department of Immunology, Genetics and Pathology, Uppsala University
Tanja Lövgren, Department of Immunology, Genetics and Pathology, Uppsala University
Gunilla Enblad, Department of Immunology, Genetics and Pathology, Uppsala University
Yumeng Mao, Department of Immunology, Genetics and Pathology, Uppsala University
Maria Ulvmar, Department Medical Biochemistry and Microbiology, Uppsala University
Patrick Micke, Department of Immunology, Genetics and Pathology, Uppsala University
Anna Nikkarinen, Department of Immunology, Genetics and Pathology, Uppsala University
Sara Mangsbo, Department of Pharmacy, Uppsala University
Stina Wickström, Department of Oncology-Pathology and Department of clinical neuroscience, Karolinska Institute, Stockholm
Magnus Essand, Department of Immunology, Genetics and Pathology, Uppsala University
Anna Dimberg, Department of Immunology, Genetics and Pathology, Uppsala University

Course coordinator: Ingrid Glimelius, ingrid.glimelius@igp.uu.se
Nations students: Diana Spiegelberg, diana.spiegelberg@igp.uu.se
Course Administrator: Marie Pettersson, marie.pettersson@regionuppsala.se