Treatment of liver cancer

Terrmin

HT24

Beskrivning

Liver cancer, specifically hepatocellular carcinoma (HCC), is a major health challenge worldwide, leading to many deaths every year. Current treatments include chemotherapy, which is known to cause severe side-effects on the gastrointestinal system (chemotherapy-induced mucositis) and the heart (chemotherapy-induced cardiotoxicity). These side-effects reduce the patients quality of life, and also often lead to a reduction in dosage of treatment or stopping the treatment alltogether. This project aims to find new ways to make chemotherapy more effective against cancer cells while minimizing its harmful effects on the body, especially the gut and the heart. The research specifically focuses on understanding how lipid metabolism and stress response within our cells influence both the effectiveness of chemotherapy and its side effects. This project will use in vitro models and in vivo studies, to investigate the effects of chemotherapy on pathways involved in lipid metabolism and stress responses in different cell types.
Studien involverar arbete med djur och du måste gå försöksdjurskursen. Den kan göras när terminen börjar.

Huvudområde

Farmaceutisk vetenskap

Ämne

Fysiologi

Typ

Laborativ studie

Företag

Uppsala Universitet

Ort/Plats

BMC

Handledarens namn

Femke Heindryckx

Handledarens e-post

Femke.Heindryckx@mcb.uu.se

Institution

Institutionen för medicinsk cellbiologi

Program

Apotekarprogrammet

Kurs

Fördjupningsprojekt i fysiologi 30 hp - 3MC333

Omfattning/hp

30hp

Hur många studenter kan antagas för detta projekt?

1

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