Projektportal

Formulation of particles for controlled release in the lung

Beskrivning

Controlled release formulations for drug delivery to the lung would facilitate new therapeutic opportunities for the inhalation area. However, the area is challenging and there are today no controlled-release formulations available in the market. Lack of these controlled delivery systems limits the development of novel pulmonary therapies. The aim of the project is to create new controlled release systems for drug delivery in the lung by surveying and evaluating the dissolution of several promising controlled release options as well as novel systems. Different methods will be used to evaluate existing and novel drug delivery systems such as deposition of inhalation powders using a modified Andersen cascade impactor and dissolution in a Transwell system, a ?Diss Profiler and single particle approach. Long term outcome of the project is novel controlled release drug delivery systems for the lungs

Huvudområde

Farmaceutisk vetenskap

Ämne

Galenisk farmaci med inriktning mot farmaceutisk teknologi

Typ

Laborativ studie

Företag

Uppsala University

Ort/Plats

Uppsala

Handledarens namn

Irès van der Zwaan and Göran Frenning

Handledarens e-post

ires.vanderzwaan@farmbio.uu.se

Omfattning/hp

30hp

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